Anant Bahadur Patel1, Pandichelvam Veeraiah1
1NMR Microimaging and Spectroscopy, Centre for Cellular and Molecular Biology, Hyderabad, Andhra Pradesh, India
Effects of alcohol exposure via oral route on cerebral metabolism is not fully understood. In this study, we have investigated glutamatergic and GABAergic metabolism in cerebral cortex in mice exposed with different dose of alcohol via intra-gastric route. Acute treatment with alcohol at higher dose increased level of cortical GABA. Alcohol exposure selectively attenuates the excitatory activity without much changes in inhibitory function.