Abstract #1848

Impact of Kurtosis Diffusion Weighted Imaging on the Detection of Liver and Kidney Abnormalities at 1.5 and 3 Tesla

Jan Hansmann¹, Andreas Lemke², Jens Wambsganss¹, Mathias Meyer¹, Miriam Reichert¹, Stefan O. Schoenberg¹, Ulrike I. Attenberger¹

¹Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Mannheim, BW, Germany; ²Computer Assisted Clinical Medicine, University Medical Center Mannheim, Mannheim, BW, Germany

Diffusion kurtosis parameter maps of the abdomen were obtained in 118 consecutive patients at 1.5 and 3 Tesla with 6 b-values (b=0-100-500-1000-1500-2000 s/mm). Kurtosis values in normal parenchyma and a variety of kidney and liver lesions (cysts, benign and malignant tumors) were assessed and compared using the Wilcoxon-Rang-Sum test. Results show statistically signifcant differences in kurtosis values between normal parenchyma and the assessed lesions. Thus, kurtosis imaging of liver and kidney lesions is feasible at 1.5 and 3 Tesla and allows for a differentiation of various lesions compared to normal parenchmya based on kurtosis values.