Jan Hansmann1, Andreas Lemke2, Jens Wambsganss1, Mathias Meyer1, Miriam Reichert1, Stefan O. Schoenberg1, Ulrike I. Attenberger1
1Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Mannheim, BW, Germany; 2Computer Assisted Clinical Medicine, University Medical Center Mannheim, Mannheim, BW, Germany
Diffusion kurtosis parameter maps of the abdomen were obtained in 118 consecutive patients at 1.5 and 3 Tesla with 6 b-values (b=0-100-500-1000-1500-2000 s/mm). Kurtosis values in normal parenchyma and a variety of kidney and liver lesions (cysts, benign and malignant tumors) were assessed and compared using the Wilcoxon-Rang-Sum test. Results show statistically signifcant differences in kurtosis values between normal parenchyma and the assessed lesions. Thus, kurtosis imaging of liver and kidney lesions is feasible at 1.5 and 3 Tesla and allows for a differentiation of various lesions compared to normal parenchmya based on kurtosis values.