Meeting Banner
Abstract #1855

Finite Element Simulation and Visualisation of Hyperpolarised Gas Diffusivity Distributions in Models of Lung Airways

Juan Parra-Robles1, Jim M. Wild1

1Academic Unit of Radiology, University of Sheffield, Sheffield, United Kingdom

In this work, we use histological sections to generate computer models of acinar airways. Using these models, finite element computer simulations of 3He and 129Xe gas diffusion in the lungs are implemented. The results of these simulations are presented here through maps of microscopic magnetization and diffusivity distributions. This approach to the simulation and visualization of the results helps provide a better understanding of the different length scales and diffusion regimes present in lung diffusion MR experiments.