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Abstract #1877

Sub-Millimeter Diffusion MRI at 7T: Does Resolution Matter?

Robin Martin Heidemann1, Alfred Anwander2, Thorsten Feiweier3, Cornelius Eichner2, Ralf Ltzkendorf4, Johannes Bernarding4, Thomas R. Knsche2, Robert Turner2

1Max Planck Institute for Human Cognitive and Brain Sciences , Leipzig, Germany; 2Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Germany; 3Siemens Healthcare Sector, Erlangen, Germany; 4Otto von Guericke University, Magdeburg, Germany

An isotropic sub-millimeter spatial resolution can be achieved in diffusion MRI using advanced acquisition strategies and hardware at 7T. It is shown that an isotropic resolution of 1 mm results in micro-structural maps with more details, especially in the cortex, compared to 1.5 mm isotropic resolution. We show results based on diffusion acquisitions with 800 m isotropic resolution, showing fine structures even in basal regions of the brain, such as the Thalamus.