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Abstract #1890

Optimal Ordering of Diffusion MRI Measurements: An Extremely Efficient and Effective Approach

Cheng Guan Koay1, Samuel A. Hurley1, M. Elizabeth Meyerand1

1Department of Medical Physics, University of Wisconsin-Madison, Madison, WI, United States

Diffusion MRI measurements are acquired sequentially with unit gradient directions that are distributed uniformly on the unit sphere. The ordering of the gradient directions has significant effect on the quality of dMRI-derived quantities. Even though several methods have been proposed to generate optimal orderings of gradient directions, these methods are not widely used in clinical studies because of the two major problems of computational inefficiency. In this work, the authors propose two extremely efficient and deterministic methods to solve these problems.