Localized High Resolution DTI of the Human Brain Using Parallel Imaging and Outer-Volume Suppression at 7T

Christopher J. Wargo¹, John C. Gore¹

In this abstract, outer volume suppression (OVS) is combined with SENSE parallel imaging to accelerate diffusion tensor imaging (DTI) in the human brain at 7T. OVS provides additional reduction in the DTI data set beyond that achieved using SENSE by constraining the FOV to localized regions in the brain, targeting specifically the midbrain, lentiform, and basal ganglia. In-plane resolutions of 1mm x 1mm x 2 mm were acquired using six diffusion directions and a b value of 1000 s/mm2. Resulting DTI-OVS images are of high quality with minimal or no artifacts using a single shot EPI sequence, enabling localized FA and ADC measurement.