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Abstract #1938

Development and Evaluation of a Simulated FiberCup Phantom

Bryce Wilkins1, Namgyun Lee1, Manbir Singh1

1Radiology and Biomedical Engineering, University of Southern California, Los Angeles, CA, United States

The FiberCup diffusion phantom, designed to mimic a coronal cross-section of the human brain, was developed for quantitative evaluation of multi-fiber diffusion models and tractography algorithms. The data available, however, is insufficient to allow comparison against all diffusion-weighted MRI methods, such as Diffusion Spectrum Imaging. We outline development of an accurate and flexible q-Space simulation of the FiberCup phantom, and illustrate its versatility by synthesizing data and processing it according to Diffusion Tensor Imaging, Diffusion Spectrum Imaging, Constrained Spherical Deconvolution and analytical Q-Ball Imaging methods. Results of tractography are presented.