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Abstract #2079

Small Scale Functional Activations Using a Non-Linear, Population-Specific Brain Model and 3D EPI at 7 Tesla

Gnther Grabner Grabner1, 2, Benedikt Andreas Poser2, Siegfried Trattnig1, Markus Barth2

1Department of Radiology, Medical University Vienna, Vienna, Austria; 2Donders Institute for Brain, Cognition and Behaviour, Radboud University Nijmegen, Nijmegen, Netherlands

Due to the availability of high field scanners and novel imaging methods, high resolution, whole brain fMRI becomes feasible. However, for performing fMRI group analyses spatial smoothing is necessary to account for inter-individual anatomical variation. Here, we investigate the possibility to build a high resolution, group specific anatomical template (model) directly from the functional T2* weighted data acquired at 7 Tesla. The purpose of this model is two fold; first, spatial smoothing can be kept at a low level and second, misregistration between distorted functional and anatomical data is avoided.