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Abstract #2109

Olfactory FMRI Connectivity Analysis Based on Granger Causality with Application in Anosmia Assessment

Elena Molina1, Susana Borromeo1, Guillermo Luna1, Jose Angel Pineda-Pardo1, Ana Beatriz Solana1, Cristina Gmez2, Adolfo Toledano3, Juan Antonio Hernndez-Tamames1

1Neuroimaging Lab., Center for Biomedical Technology - Universidad Politcnica de Madrid and Universidad Rey Juan Carlos, Pozuelo de Alarcn, Madrid, Spain; 2CC. Salud Universidad Rey Juan Carlos, Mstoles, Madrid, Spain; 3Servicio Otorrino Fundacin Hospital de Alcorcn, Alcorcn, Madrid, Spain

In this work, we describe hubs organization within the olfactory network with Functional Magnetic Resonance Imaging (fMRI). Granger causality analyses were applied in preselected regions of interest (ROIs) involved in olfactory tasks. We found differences between healthy subjects and patients with different types of anosmia: viral, idiopathic and traumatic. The study of the hubs organization conducted us to an accurate description of the strength of the nodes within the olfactory network and which of them are impaired in different anosmic pathologies.