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Abstract #2138

Differential Consolidation of Motor Memory

Kuang-Chi Tung1, Jinsoo Uh1, Hanzhang Lu1

1Advanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX, United States

Resting brain encodes footprint of training effect. The spatial pattern of increase in the amount of spontaneous activity and functional connectivity are strikingly different, based on the amount of neural activity involved during the training. Our present findings show that in two-hand training, consolidation of training effect took place in frontal lobe and mid-brain regions such as hypothalamus and basal nuclei, whereas in one-hand training, it took place primarily in the motor and somatosensory areas.