Abstract #2162

fMRI/fcMRI Investigation Showing Cortical and Subcortical Pathways Involving in Phrenic Nerve Activation and Respiration Control in Rats Under 9.4Tesla.

Rupeng Li¹, Nicholas Flugstad², Xiping Liu³, Christopher Pawela¹,², Ji-Geng Yan², Hani S. Matloub², James S. Hyde¹

¹Biophysics, Medical College of Wisconsin, Milwaukee, WI, United States; ²Plastic Surgery, Medical College of Wisconsin, Milwaukee, WI, United States; ³Anesthesiology, Medical College of Wisconsin, Milwaukee, WI, United States

Cortical and subcortical pathways accouting for phrenic nerve function were discovered with the combination of BOLD fMRI and fcMRI for the first time.It helps with further investigation of respiratory system control and provide physiological basis for this nerve to be used as donor for peripheral nerve injury repair.