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Abstract #2175

Frequency Cutoff in Neurovascular Coupling of Resting-State FMRI

Wen-Ju Pan1, Garth Thompson1, Matthew Magnuson1, Shella Keilholz1

1Biomedical Engineering, Emory University/Georgia Institute of Technology, Atlanta, GA, United States

BOLD fluctuations typically exhibit high power only in the low frequencies (<0.1). The mechanism of the frequency cutoff has been rarely investigated. By simultaneous intracortical DC recording and fMRI, the DC/BOLD coherences were demonstrated within a frequency range of high BOLD power, and can be modulated by vasoactive properties in a rat model.