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Abstract #2281

Reconstruction of Accelerated Dynamic Contrast-Enhanced Lung MR Imaging Using Phase-Correlation Motion Estimation and Motion Compensation

Mei-Lan Chu1, Jia-Shuo Hsu1, Hsiao-Wen Chung1, Shang-Yueh Tsai2, 3, Yi-Ru Li4

1Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan; 2Graduate Institute of Applied Physics, National Chengchi University, Taipei, Taiwan; 3Research Center for Mind, Brain and Learning, National Chengchi University, Taipei, Taiwan; 4Department of Electronic Engineering, National Taiwan University of Science and Technolo, Taipei, Taiwan

Phase-correlation motion estimation (ME) and motion compensation (MC), which is an essential part of video compression technique, has been successfully applied to reconstructing under-sampled cine cardiac imaging. For dynamic MR imaging outside of the cardiac region, such as dynamic contrast-enhanced (DCE) perfusion lung imaging, higher temporal resolution for wider slice coverage is still highly desirable. In this abstract, we demonstrate that the drawbacks of temporal-smoothing and baseline overshoot can be overcome by using phase-correlation ME / MC with 2-fold to 6-fold acceleration. The experimental results show that the proposed method successfully reconstructs full-resolution dynamic frames at substantially reduced acquisition data without the disadvantages of overshooting in the initial time frames and the undesired smoothing effects in the presence of abrupt temporal variations.