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Abstract #2291

Gradient Localized (GradLoc) Parallel Imaging Using a 3-D Magnetic Encoding Field with a Quadratic-Phase RF Pulse to Precompensate for Through-Slice Dephasing

Jason P. Stockmann1, Gigi Galiana2, R. Todd Constable1, 2

1Biomedical Engineering, Yale University, New Haven, CT, United States; 2Diagnostic Radiology, Yale University, New Haven, CT, United States

Quadratic phase has been shown to permit spatial localization by "phase scrambling" signals from outside a given region of interest. This has been applied in the through-slice direction using quadratic-phase RF pulses as well as in-plane using nonlinear spatial encoding magnetic fields. In this work, we use a quadratic-phase RF pulse to precompensate the through-plane phase applied by a 3-D magnetic encoding field, permitting acquisition of the target region-of-interest using a Z2 spherical harmonic field. We further show that GradLoc can be combined with parallel imaging to enable highly-accelerated acquisitions of the region of interest without aliasing.