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Abstract #2314

Single-Sequence Single-Quantum and Triple-Quantum Imaging of Sodium at Ultra-High Field Strengths

Daniel P. Fiege1, Sandro Romanzetti1, Fernando E. Boada2, Stephen R. Yutzy2, Yongxian Qian2, Jrg Felder1, N. Jon Shah1, 3

1Institute of Neuroscience and Medicine - 4, Forschungszentrum Jlich, Jlich, Germany; 2Radiology and Bioengineering, University of Pittsburgh, Pittsburgh, PA, United States; 3JARA - Faculty of Medicine, RWTH Aachen University, Aachen, Germany

Sodium levels are tightly regulated in the human body. Therefore monitoring total sodium and triple-quantum filtered sodium (as a measure of intracellular sodium) are of great interest for a variety of diseases of the central nervous system. A sequence that enables acquisition of tissue sodium concentration weighted and triple-quantum filtered sodium images in the same run is presented, using two different TPI readouts. Phantom and in vivo results from 9.4T show very good resolution and SNR.