Superfast Dipole Inversion (SDI) for Real-Time Quantitative Susceptibility Mapping (QSM)

Ferdinand Schweser¹, Andreas Deistung¹, Karsten Sommer¹, Jrgen Rainer Reichenbach¹

Magnetic susceptibility is an intrinsic physical tissue property, which recently became accessible in vivo by quantitative susceptibility mapping (QSM). The practical applicability of QSM, however, is currently hampered by the enormous numerical complexity and computational cost associated with the QSM reconstruction. In this study, we present and analyze a novel QSM framework, Superfast Dipole Inversion (SDI), that not only allows reconstruction of susceptibility maps from raw gradient-echo phase data in near real-time, but also enables processing of phase images with open-ended fringe lines, which often occur in practice due to improper combination of multi-channel images and which have hitherto hindered QSM.