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Abstract #2375

Anatomically Induced Regularization of Myelin Water Estimation by DW-MRI

Milos Ivkovic1, Thanh Nguyen1, Dushyant Kumar2, Susan Gauthier2, Ashish Raj2

1Weill Cornell Medical College, New York City , NY , United States; 2Weill Cornell Medical College, New York City, NY, United States

We propose a spatially adaptive filter, based on the Diffusion-Weighted MRI, that regularizes T2 relaxometry signal with respect to neuronal direction -information otherwise unavailable in T2 relaxometry. Similar approaches can be used with other myelin content estimation techniques.