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Abstract #2384

A Theoretical Framework for DANTE Prepared Pulse Trains: A Novel Approach to Motion Sensitized and Motion Suppressed Quantitative MRI

MAGNA25Linqing Li1, Karla Miller1, Peter Jezzard1

1FMRIB, Clinical Neurology Department, University of Oxford, Oxford, United Kingdom

DANTE (a rapid series of low flip angle RF pulses interspersed with gradients)pulse trains may be employed for flow fluid signal suppression module. During application of DANTE pulse trains, longitudinal magnetization of flowing spins is largely (or fully) attenuated due to phase dispersion accrued while flowing along the applied gradient. This is in contrast to static tissue, whose longitudinal magnetization is mostly preserved. This progressive saturation of flowing spins is insensitive to velocity (above a threshold). This work is a theoretical framework for motion sensitized and motion suppressed quantitative MRI when DANTE is applied.