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Abstract #2523

Effect of Stretching and Compression on the Dynamic Shear Modulus Using MRE

Remy Blanchard1, Yogesh K. Mariappan2, Richard L. Ehman2, Denis Grenier1, Elisabeth Brusseau1, Olivier Basset1

1Universit de Lyon, CREATIS ; CNRS UMR5220 ; Inserm U1044 ; INSA-Lyon ; Universit Lyon 1, Lyon, France; 2Department of Radiology, Mayo Clinic, Rochester, MN, United States

The goal of this study was to analyze the effect of controlled compression and tension on the dynamic shear modulus for the two directions of wave propagation orthogonal to the particle motion. These mediums were a 100% PVC phantom and an ex vivo specimen of bovine liver. For both the phantom and the specimen, the measured shear modulus in both directions increases with the absolute value of the axial strain under both compression and tension. This data provide motivation to further investigate the effects of pre-strain and their clinical utility to improve the information obtained from MRE.