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Abstract #2716

Simultaneous Diffusion, Perfusion MRI and FET-PET

Ke Zhang1, Irene Neuner1, 2, Christian Filss1, Karl-Josef Langen1, Hans Herzog1, Nadim Joh Shah1, 3

1Institute for Neuroscience and Medicine Medical Imaging Physics, Medical Imaging Physics (INM-4), Forschungszentrum Jlich, Jlich, Germany; 2Faculty of Medicine, Department of Psychiatry and Psychotherapy, JARA, RWTH Aachen University, Aachen, Germany; 3Faculty of Medicine, Department of Neurology, JARA, RWTH Aachen University, Aachen, Germany

PET with metabolic imaging is the clinical established technique for the diagnosis of cerebral gliomas. Diffusion MRI is the anatomical tool to demonstrate the plasticity of the brain. Perfusion MRI can precisely investigate the angiogenesis in the tumour and help classify and grade brain tumours. In this study, diffusion, perfusion MRI and FET-PET were simultaneously acquired using a hybrid 3T MR-PET scanner. Using the hybrid approach, data from two representative human brain tumour cases are presented. The results demonstrates that hybrid technique offers fast, complete and valuable information for diagnosis and neurosurgery of brain tumours.