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Abstract #2723

MR-Based FoV Extension of Human Attenuation Correction in Whole-Body MR/PET Hybrid Imaging

Jan Ole Blumhagen1, 2, Ralf Ladebeck1, Matthias Fenchel1, Harald H. Quick3, Klaus Scheffler2, 4

1Magnetic Resonance, Siemens Healthcare, Erlangen, Bavaria, Germany; 2Division of Radiological Physics, University of Basel Hospital, Basel, Switzerland; 3Institute of Medical Physics, Friedrich-Alexander-University Erlangen-Nrnberg, Erlangen, Germany; 4MRC Department, Max Planck Institute for Biological Cybernetics, Tbingen, Germany


In whole-body MR/PET, the human tissue attenuation correction (AC) of PET data can be based on the MR data. However, the MR FoV is limited due to B0 inhomogeneities and gradient nonlinearities. Therefore, the human AC map may be truncated and thus the PET reconstruction may be biased. In this work we explored extending the MR-based AC map using a purely MR-based FoV extension. We applied this method to whole-body MR/PET examinations on patients and evaluated the impact on the PET reconstruction. The reported bias was reduced and the PET reconstruction was in good agreement with a PET/CT reference measurement.