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Abstract #2904

Evaluation of a New QBOLD Approach to Map Local Blood Oxygen Saturation in Non Human Primates

Julien Bouvier1, 2, Affif Zaccaria1, 3, Irne Troprs4, Laurent Selek3, 5, Pierre Bouzat3, 5, David Chechin2, Franois Berger3, 5

1INSERM, U836, Grenoble, Isre, France; 2Philips Healthcare, Suresnes, Ile de France, France; 3Universit Joseph Fourier, Grenoble Institute of Neurosciences, Grenoble, France; 43T Facility, SFR Biomedical NMR and Neurosciences, Grenoble, France; 5CHU, Grenoble, France

Tissue oxygenation can be characterized by local oxygen saturation (lSO2), which may be mapped by quantitative Blood Oxygen Level Dependent (BOLD) approaches. An approach that combines separate estimates of T2, T2*, BVf, and B0 inhomogeneities has recently been proposed and validated in rats and a preliminary study has been realized in humans. The aim of this study is to evaluate this approach in non human primates under two depth of anesthesia.