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Abstract #2906

Brain Oxygen Saturation Assessment Using T2 Prepared Diffusion Imaging

Esben Thade Petersen1, Jill De Vis1, Thomas Alderliesten2, Petra M. Lemmers2, Karina J. Kersbergen2, Manon Benders2, C. A. T. van den Berg3, Jeroen Hendrikse1

1Department of Radiology, UMC, Utrecht, Netherlands; 2Neonatology, Wilhemina Children's Hospital, Utrecht, Netherlands; 3Department of Radiotherapy, UMC, Utrecht, Netherlands

Bloods oxygen saturation is an important parameter for the evaluation of patients such as stroke or asphyxiated newborns. Here we present a method for measurement of blood T2 in the tissue using a T2-Prepared Blood IVIM Imaging of Oxygen Saturation (T2-BIOS) sequence from where bloods oxygen saturation can be estimated. IVIM effects in diffusion-weighted imaging are exploited to separate the blood signal and by using previous determined relationships of T2 versus Y, one can generate an oxygen saturation map. In the neonates this information is obtained from NIRS and similarity is shown, although not significantly correlated in this small population.