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Abstract #2918

Compressed Sensing for Accelerated MR Thermometry in MRI-Controlled Transurethral Ultrasound Therapy

Patrick Leonard1, 2, Rajiv Chopra, 12, Adrian Nachman3, 4

1Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 2Sunnybrook Research Institute, Toronto, Ontario, Canada; 3Department of Electrical Engineering, Universisty of Toronto; 4Department of Mathematics, Universisty of Toronto

In the current implementation of MRI-controlled transurethral ultrasound therapy the 3D spatial heating pattern is approximated by a series of 2D slices acquired every 5 7 seconds. Knowledge of the true 3D temperature distribution could allow for more sophisticated temperature control algorithms and improve the monitoring of nearby tissues for safety. In this work we examine the use of compressed sensing as a means of accelerating the data acquisition time, where preserving the quantitative accuracy of the temperature measurements is critical. Our results show that our treatment remains safe and effective at up to 32-fold acceleration rates.