Abstract #2940

Intrapericardial Delivery of Imaging-Visible Microencapsulated Mesenchymal Stem Cells Using XFM Guidance

Yingli Fu¹, Nicole Azene², Tina Ehtiati³, Aaron Flammang³, Wesley Gilson³, Judy Cook⁴, Kathleen Gabrielson², Clifford Weiss⁴, Jeff W. Bulte⁴, Peter V. Johns

¹Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD, United States; ²Molecular & Comparative Pathobiology, Johns Hopkins University, Baltimore, MD, United States; ³Siemens Corporate Research, Baltimore, MD, United States; ⁴Radiology, Johns Hopkins University, Baltimore, MD, United States; ⁵Department of Medicine, Johns Hopkins University, Baltimore, MD, United States

X-ray fused with magnetic resonance imaging (XFM) takes advantage of both imaging modalities allowing cardiac function assessments and direct visualization of the vasculature. XFM guided microencapsulated stem cell delivery into the pericardium space was safe and would improve the retention of cellular therapeutics in the heart.