Quality Assurance of the Multi-Center Trial Prostate Cancer Localization with a Multiparametric MR Approach (PCaMAP): Initial Results

Marnix C. Maas¹, Jurgen J. Ftterer², Tom W.J. Scheenen²

Quality assurance measurements were performed for a prospective study involving 10 institutions, aimed at proving the diagnostic accuracy of 3T multi-modality MR imaging including high-resolution T2-weighted imaging, DWI, DCE and 3D MRSI in distinguishing carcinoma from other prostate tissue. ADCs, T₁s and (Choline + Spermine + Creatine) / Citrate ratios were compared in 5 institutions in this preliminary study. Modest but statistically significant differences between institutions were found in all 3 categories. Whether this warrants corrections of the quantitative data for the prospective study will be subject to further investigation.