Abstract #3089

Therapeutic Activity of a New Targeted Theranostic Agent for the Peri-Infarct Region in Stroke

Jess Agulla¹, David Brea¹, Mara Prez-Mato¹, Miguel Blanco¹, Jos Castillo¹, Pedro Ramos-Cabrer¹

¹Clinical Neuriosciences Research Laboratory, Department of Neurology, University Clinical Hospital, University of Santiago de Compostela, Santiago de Compostela, Spain

In this work we study the therapeutic capability of a theranostic agent targeted against cells of the peri-infarct tissue in stroke. We treated ischemic animals with targeted theranostic molecules doped with citicoline. We compare the therapeutic effects of these molecules with those induced by free administered citicoline, citicoline encapsulated in non-targeted liposomes and the respective controls.