Abstract #3094

Longitudinal Perfusion Change After Intracranial Stem Cell Implantation in Chronic

Chao-Chun Lin¹,², Wu-Chung Shen¹, Yung-Jen Ho¹, Yu-Chien Lo¹, Po-Pang Tsai¹, Chia-Wei Lin¹, Chiao-Ying Wu¹, Hing-Chiu Chang²,³, Hsiao-Wen Chung<s

¹Radiology, China Medical University Hospital, Taichung, Taiwan; ²Graduate Institute of Biomedical Engineering and Bioinformatics, National Taiwan University, Taipei, Taiwan; ³Applied Science Laboratory, GE Healthcare, Taipei, Taiwan; ⁴Electrical Engineering, National Taiwan University, Taipei, Taiwan; ⁵Center for Neuropsychiatry and Graduate Institute of immunology, China Medical University Hospital, Taichung, Taiwan; ⁶Neurosurgery, China Medical University Beigang Hospital, Beigang, Taiwan

This study is to longitudinal follow up the perfusion change after intracranial stem cell implantation in chronic stroke patient. Our preliminary result shows temporally increase cerebral blood flow and volume which then decrease and are lower than the baselines in the long-term follow up. The perfusion change is earlier than the clinical neurologic symptoms improvement which began from the 3months after stem cell implantation.