Meeting Banner
Abstract #3127

Presentations of Multiple Sclerosis Lesions on Quantitative Susceptibility Mapping (QSM)

Weiwei Chen1, Tian Liu2, Joseph Comunale3, Susan Gauthier3, Linda Heier3, Apostolos Tsiouris3, Tim Vartarian3, Yi Wang3, 4

1Tongji Hospital, Tongji Medical College, Huazhong University of Science& Technology (HUST), Wuhan, Hubei, United States; 2MedImageMetric LLC, New York, NY, United States; 3Weill Cornell Medical College, New York, NY, United States; 4Biomedical Engineering, Cornell University, Ithaca, NY, United States

19 consecutive MS patients were imaged on a 3T MRI system using T2FLAIR, gradient echo (GRE) and CET1W sequences. QSM was reconstructed from GRE data. A total of 203 lesions were identified on T2FLAIR, and their presentations on QSM were characterized according to their signal value and geometry. Frequently observed MS lesion presentations on QSM include 1) positive with associated veins only (35.5%), 2) not present (25.6%), 3) positive without associated veins or surrounding positive ring (20.7%), and 4) positive with both associated veins and a surrounding positive ring (8.4%).