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Abstract #3130

Magnetic Field Correlation Imaging of Brain Iron in Attention-Deficit/Hyperactivity Disorder

MAGNA25Vitria Adisetiyo1, 2, Rachael L. Deardorff3, Ali Tabesh3, Els Fieremans2, Amanda Allen3, Rebecca Grzadzinski4, Adriana Di Martino4, Francisco X. Castellanos4

1Neuroscience & Physiology, NYU School of Medicine, New York, NY, United States; 2Radiology, NYU School of Medicine, New York, NY, United States; 3Radiology, Medical University of South Carolina, Charleston, SC, United States; 4NYU Child Study Center, NYU School of Medicine, New York, NY, United States

Attention-Deficit/Hyperactivity Disorder (ADHD) has been associated with lower serum iron levels that correlate to symptom severity but there is only one study that has looked into brain iron in ADHD. We have applied a novel imaging method called Magnetic Field Correlation Imaging (MFC) to investigate brain iron in ADHD compared to typically developing controls (TDC). Conventional measures of R2 and R2* as well as serum iron measures were also acquired. Although there were no differences detected in serum iron measures, significantly lower brain iron was found in the globus pallidus and caudate nucleus in the ADHD group. Only MFC measures were able to detect this group difference.