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Abstract #3171

DTI in Neonates: Data Corruption Due to Motion

Anneriet M. Heemskerk1, 2, Annemarie Plaisier2, Irwin Reiss2, Maarten H. Lequin1, Alexander Leemans3, Jeroen Dudink, 12

1Radiology, Erasmus MC University Medical Center, Rotterdam, Netherlands; 2Pediatrics, Erasmus MC University Medical Center, Rotterdam, Netherlands; 3Image Sciences Institute, University Medical Center Utrecht, Utrecht, Netherlands

Motion corrupted slices are a major problem in neonatal DTI as neonates have high occurrence of movement and this motion results in corrupted slices. We investigate the number of outliers in the tensor estimation as a method to detect corrupted slices in neonates. We found that 60% of the 27 subjects had corrupted data, defined as >10 slices with >30% outliers. These corrupted slices can lead to registration problems and erroneous tensor estimates depending on their location and spread. Targeted acquisition and processing is needed in this specific subject group to obtain reliable tensor estimates.