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Abstract #3255

Intra and Inter-Subject Reproducibility of Fully Adiabatic 31P GOIA-1D-ISIS/2D-CSI (GoISICS) in Calf Muscle at 7T.

Marek Chmelik1, Ivica Just Kukurova2, 3, Stephan Gruber2, Martin Krk4, Ladislav Valkovic2, Siegfried Trattnig2, Wolfgang Bogner2

1MR Centre of Excellence, Dept. Radiology , Medical University of Vienna, Vienna, Austria; 2MR Centre of Excellence, Dept. Radiology, Medical University of Vienna, Vienna, Austria; 3Department of NMR and MS, Institute of Analytical Chemistry, Slovak University of Technology, Bratislava, Slovakia; 4Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

As recently described 31P 2D-CSI based on GOIA-1D-ISIS/2D-CSI (goISICS) enables fully adiabatic acquisition with minimal chemical shift displacement error at 7T. The purpose of this study was to analyze intra- and inter-subject variability of goISICS in the calf muscle at 7T. Both, inter and intra-subject reproducibility measurements showed comparable high quality spectra in a distance of 2.5 cm and 5 cm from the surface coil and slightly lower quality in a distance of 7.5cm.The reproducibility was high for pH, γ-NTP/PCr , α-NTP/PCr and Pi/PCr and lower for β-NTP/PCr, PDE/PCr and PME/PCr.