Meeting Banner
Abstract #3300

Study of the Vertical Striations in Articular Cartilage Using Dipolar Anisotropy Fiber Imaging

Nikolaus M. Szeverenyi1, Jiang Du1, Chantal Pauli2, Sheronda Statum1, Christine Chung1, Graeme M. Bydder1

1Radiology, University of California, San Diego, CA, United States; 2Scripps Institute, San Diego, CA, United States

Magic angle effects are important in accounting for the signal of different layers of articular cartilage, but equally striking are vertical striations seen perpendicular to the layers. These correlate with leaves seen with freeze-fracture, but the mechanism responsible for contrast between them has not been defined. By systematically rotating cartilage relative to B0, imaging it, registering the images and studying the signal intensity, differences in degree of magic angle effect between leaves were defined. In addition, both linear and meshwork patterns of fibers were demonstrated in the leaves. These structures were most evident in uncovered cartilage.