Abstract #3394

Dogs Whole Brain Probabilistic Diffusion Tensor Imaging Tractography Normalization: A Solution for Brain Image Normalization Difficulty Problems

Witaya Sungkarat¹, Jiraporn Laothamatas¹, Boonlert Lumlertdacha², Supaporn Wacharapluesadee³, Thiravat Hemachudha⁴

¹Advanced Diagnostic Imaging and Image-Guided Minimal Invasive Therapy Center and Radiology Dept., Ramathibodi Hospital Faculty of Medicine, Mahidol University, Rajataewe, Bangkok, Thailand; ²Queen Saovabha Memorial Institute, Thai Red Cross Society, Bangkok, Thailand; ³WHO Collaborating Center for Research and Training on Viral Zoonoses, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand; ⁴Department of Medicine and WHO Collaborating Center for Research and Training on Viral Zoonoses, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand

A new normalization technique using whole brain probabilistic DTI tractography maps is presented. This technique can address immense brain variability, even in dogs brains. Both FSL and SPM2 were used. The usefulness of the technique was demonstrated in conducting voxel-based group analyses of FA and MD maps of rabid and normal dogs.