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Abstract #3419

3D Quantitative Imaging of Relaxation Parameters of Whole Brain

Weitian Chen1, Patrick D. Koon2, Ajit Shankaranarayanan1

1Global MR Applied Science Laboratory, GE Healthcare, Menlo Park, CA, United States; 2GE Healthcare, San Francisco, CA, United States

Quantification of T2 or T1rho in brain can provide additional diagnostic information to anatomy images. A major challenge to such quantification methods is very long scan time in order to achieve high resolution with 3D coverage of the brain. In this work, we investigated fast 3D quantitative T1rho or T2 imaging of whole brain based on highly SNR efficient 3D fast spin echo acquisition. We reported a simple method to reduce adversary eddy current effect in the developed pulse sequence. The T2-weighted image contrast can be utilized for simultaneous anatomical imaging besides T1rho or T2 quantification.