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Abstract #3429

Real-Time Correction by Optical Tracking with Integrated Geometric Distortion Correction by PLACE for Reducing Motion Artifacts in FMRI: In-Vivo Experiments

David Rotenberg1, 2, Mark Chiew1, 2, Fred Tam1, 3, Shawn Ranieri1, Simon Graham, 23

1Rotman Research Institute, Toronto, Ontario, Canada; 2Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; 3Physical Sciences Sunnybrook Research Institute, Toronto, Ontario, Canada

Head motion artifacts are a substantial source of error in Blood Oxygen Level Dependent fMRI that limits its use in neuroscience research and clinical settings. Real-time scan-plane correction by optical tracking has been shown to suppress artifacts due to slice-misalignment and non-linear spin-history effects, however, residual artifacts due to dynamic magnetic field non-uniformity may remain in the data. We demonstrate a novel correction approach that integrates volume by volume, geometric distortion correction by PLACE into a real-time scan-plane update system by optical tracking, applied to an fMRI finger tapping experiment with overt head motion to induce dynamic field non uniformity.