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Abstract #3482

Estimation of Breast Tumor Conductivity Using Parabolic Phase Fitting

Ulrich Katscher1, Karim Djamshidi1, Tobias Voigt2, Marko Ivancevic3, Hiroyuki Abe4, Gillian Newstead4, Jochen Keupp1

1Philips Research Europe-Hamburg, Hamburg, Germany; 2Philips Research Europe-Aachen, Aachen, Germany; 3Philips Healthcare, Cleveland, United States; 4University of Chicago, Chicago, United States

Ex Vivo studies exhibited significantly altered electric conductivity of breast tumors, opening the chance to increase the specificity of breast tumor characterization. Conductivity can be measured in vivo using Electric Properties Tomography (EPT), which has shown its potential in phantom, volunteer, and initial clinical studies. However, the complex frayed structure of fat and ductile tissue in the breast hampers the straight-forward application of EPT, based on the second derivative of the RF TX phase. In this study, a new EPT reconstruction via fitting local parabolic functions on the TX phase is developed and applied to an example breast tumor.