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Abstract #3498

In Vivo Blood T1 Measurements at Different Field Strengths: How Much Do We Gain in ASL by Moving to Higher Field Strengths?

Xingxing ZHANG1, Esben T. Petersen2, 3, Eidrees Ghariq1, Jill de Vis2, Andrew G. Webb1, Wouter M. Teeuwisse1, Jeroen Hendrikse2, Matthias J.P. van Osch1

1The C.J.Gorter Center for High Field Magnetic Resonance, Leiden University Medical Center, Leiden, Zuid-Holland, Netherlands; 2Department of Radiology, University Medical Center Utrecht, Utrecht, Netherlands; 3Department of Radiotherapy, University Medical Center Utrecht, Utrecht, Netherlands

Blood T1 is a crucial parameter in the ASL technique, especially for the quantification of CBF. The increase in blood T1 at higher field strengths is one of the main presumed advantages of ASL at higher field MRIs. In this study the blood T1 was measured in the sagittal sinus at three different field strengths: 1.5T, 3T and 7T. The main findings were that the T1 increased linearly with field strength and that the T1 at 7T (2087ms) was lower than previously reported.