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Abstract #3560

Optimal B-Value Range in Diffusion Kurtosis Imaging

Ezequiel Farrher1, Farida Grinberg1, N. Jon Shah1, 2

1Institute of Neuroscience and Medicine - 4, Forschungszentrum Juelich, Juelich, Germany; 2JARA - Faculty of Medicine, RWTH Aachen University, Aachen, Germany

In the recent years, diffusion kurtosis imaging has become an important method for the quantification of the non-Gaussian diffusion in brain tissue by means of magnetic resonance imaging. In this work we carry out an experimental investigation of the optimal allowed range of b-values according to the type of tissue under examination and an applied set of gradient directions. We examine how the mean-diffusivity and mean-kurtosis maps are influenced by the chosen range of b-values and propose an optimization scheme.