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Abstract #3593

Comparison of in vivo Human, in vivo Macaque and ex vivo Human Measurements of Diffusion Orientation in the Cerebral Cortex

Jennifer A. McNab1, Jonathan R. Polimeni1, Ruopeng Wang1, Jean C. Augustinack1, Kyoko Fujimoto1, Allison Player1, Christina Triantafyllou1, 2, Thomas Janssens3

1A.A. Martinos Center for Biomedical Imaging, Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, United States; 2A.A. Martinos Center at the McGovern Institute for Brain Research, Massachusetts Institute of Technology, Cambridge, MA, United States; 3Laboratory for Neuro- and Psychophysiology, K.U. Leuven Medical School, Campus Gasthuisberg, Leuven, Belgium; 4Harvard-MIT Health Sciences and Technology Division, Massachusetts Institute of Technology, Cambridge, MA, United States

We compare cortical diffusion anisotropy in in vivo human (1 mm iso), in vivo macaque (0.7 mm iso) and in ex vivo human tissue (0.5 mm iso). All data sets show radial diffusion in M1 and tangential diffusion in S1, although the ex vivo human data also shows some regions of radial diffusion in S1.