able according additionally adjustment advanced advantages affect allows amount anatomical approaches architectonic atlas automatic become brandy cancer centroids classification classified classifies clustering clusters coded colleagues color comp compartments completely connected connectivity considered consists contrast correct cortex cortical depends detail detected determine determined difficult diffusion disadvantages discussed dominant driven eigenvector elongated enough errors example exploring fast features fiber filters find fixed focus forward full gained generated gives going heuristically identify individual initialize interpretation invasive knowledge known local makes masking measures need needed needs noise nuclear nuclei orientation outline overview part popular population principal prior probabilistic processing produce profile proposed proximity qualities quality reason reasonable recent registration render renderings reproducible reproduction require required requires restricted return role rough seeded segmentation segmented selecting several shape similarity simple smith space spatial spatially special split staining station straight structure structures studies subject summary surface susceptible table tend tensor tensors thalamus tool tracking tuning types whole years