Meeting Banner
Abstract #3632

MRI Biomarkers Capable of Detecting Effects of an Experimental Pharmacologic Therapy for Idiopathic Normal Pressure Hydrocephalus

Milos Ivkovic1, Heather Katzen2, Ilhami Kovanlikaya3, Ahmet Bagci2, Linda Heier3, Noam Alperin2, Ashish Raj3, Norman Relkin3

1Weill Cornell Medical College, New York City , NY , United States; 2University of Miami School of Medicine, Miami, FL; 3Weill Cornell Medical College, New York City, NY, United States

There are no proven pharmacologic treatments for Normal Pressure Hydrocephalus (NPH). Acetazolamide (ACZ) is known to reduce CSF production and interstitial edema. We hypothesized that a low dose of ACZ would reduce CSF production and brain interstitial fluid in NPH.