Abstract #3679

Contributions of In-Plane CSF Flow to the Derivation of Intracranial Compliance: A Three-Direction Cine Phase-Contrast Flow Study.

Yi-Ying Wu¹,², Yu-Wei Tang³, Hsu-Hsia Peng⁴, Cheng-Wen Ko⁵, Cheng-Wen Ko⁵, Hsiao-Wen Chung, Teng-Yi Huang³

¹Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei,Taiwan, Taiwan; ²National Taiwan University, Taipei,Taiwan, Taiwan, Taiwan; ³National Taiwan University of Science and Technology; ⁴National Tsing Hua University; ⁵Computer Science and Engineering, National Sun Yat-Sen University

Previous studies have proposed noninvasive phase-contrast flow mapping magnetic resonance imaging method to estimate ICC based on blood/CSF flow rates and CSF pressure gradient. Assuming that the CSF flow direction is mainly caudocranial in the spinal canal at the measurement sites, the phase-contrast technique needs to be applied with only one velocity encoding direction, which greatly shortens the scan time. In this study, we attempted to verify this assumption by using three-direction measurements to examine the contributions of various terms that might cause estimation inaccuracies in MR imaging-based ICC measurements.