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Abstract #3696

VBM Study of Diurnal Variations of Brain Diffusion in Healthy Adults

Chunxiang Jiang1, Lijuan Zhang*1, Xiaojing Long1, Weiqi Liao1, Wenhui Huang1

1Shenzhen Institutes of Advanced Technology,Chinese Academy of Sciences, Shenzhen, Guangdong, China

Diurnal alteration of diffusion parameters were observed in grey and subgyral white matter of healthy human brain. Peak ADC changes were found to locate in bilateral occipital lingual and calcarine regions while peak FA changes were located in the frontal lobes. Changes in brain diffusion parameters may reflect the underlying circadian physiological variations of human brain.