Abstract #3782

Toward Assessment of Iron Overload Diseases at 7.0 T: Myocardial T2* Mapping to Derive Global and Segmental T2* Norm Values for Healthy Subjects at 7.0 T

Fabian Hezel¹, Antonella Meloni², Jeanette Schulz-Menger¹,³, Petra Keilberg², Peter Kellman⁴, Massimo Lombardi², Thoralf Niendorf¹,³

¹Berlin Ultrahigh Field Facility, MDC Berlin, Berlin, Germany; ²Cardiovascular MR Unit, Fondazione G. Monasterio CNR-Regione Toscana and Institute of Clinical Physiology, Pisa, Italy; ³Experimental and Clinical Research Center (ECRC), Charit Campus Buch, Humboldt-University, Berlin, Germany; ⁴Laboratory of Cardiac Energetics, National Institutes of Health/NHLBI, Bethesda, MD, United States

Myocardial T2* mapping is of proven clinical value for the detection of iron overload. Ultrahigh field (>7T) offer a gain in susceptibility sensitivity, however T2* relaxation rates of healthy myocardium obtained at 1.5T and 3.0T need to be revised. This study aims to determine T2* relaxation times for normal myocardium (global and segmental) in healthy subjects with the ultimate goal to establish a lower limit of normal T2* at 7.0T.