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Abstract #3782

Toward Assessment of Iron Overload Diseases at 7.0 T: Myocardial T2* Mapping to Derive Global and Segmental T2* Norm Values for Healthy Subjects at 7.0 T

Fabian Hezel1, Antonella Meloni2, Jeanette Schulz-Menger1, 3, Petra Keilberg2, Peter Kellman4, Massimo Lombardi2, Thoralf Niendorf1, 3

1Berlin Ultrahigh Field Facility, MDC Berlin, Berlin, Germany; 2Cardiovascular MR Unit, Fondazione G. Monasterio CNR-Regione Toscana and Institute of Clinical Physiology, Pisa, Italy; 3Experimental and Clinical Research Center (ECRC), Charit Campus Buch, Humboldt-University, Berlin, Germany; 4Laboratory of Cardiac Energetics, National Institutes of Health/NHLBI, Bethesda, MD, United States

Myocardial T2* mapping is of proven clinical value for the detection of iron overload. Ultrahigh field (>7T) offer a gain in susceptibility sensitivity, however T2* relaxation rates of healthy myocardium obtained at 1.5T and 3.0T need to be revised. This study aims to determine T2* relaxation times for normal myocardium (global and segmental) in healthy subjects with the ultimate goal to establish a lower limit of normal T2* at 7.0T.