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Abstract #3842

3D Cine MRI of Mouse Heart with Concurrent Dephasing and Excitation

Naoharu Kobayashi1, Qiang Xiong2, Joseph Ippolito2, Jianyi Zhang2, Michael Garwood1

1Center for Magnetic Resonance Research, University of Minnesota, Minneapolis, MN, United States; 2Cardiology, University of Minnesota Medical School, Minneapolis, MN, United States

3D magnetic resonance cine imaging of the mouse heart is highly challenging due to limited spatial and temporal resolution and cardiac and respiratory motion. We demonstrate CODE 3D cine MRI of mouse heart with prospective electrocardiogram gating, where the matrix size was cut down to reduce TR while keeping preferable spatial resolution by using a small surface coil and oversampled acquisition. And we applied sliding window reconstruction in order to increase the nominal temporal frame rate of the cine images. This method enabled high resolution 3D cine imaging with ~23 min at 9.4T.