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Abstract #3890

Steady-State First-Pass Perfusion (SSFPP): A 3D "TWIST" in Myocardial First-Pass Perfusion Imaging

Shivraman Giri1, Hui Xue2, Abdul Wattar1, Yu Ding1, Randall Kroeker3, Gerhard Laub4, Peter Kellman5, Sven Zuehlsdorff6, Subha V. Raman1, Orlando P. Simonett

1The Ohio State University, Columbus, OH, United States; 2Siemens Corporate Research, Princeton, NJ, United States; 3Siemens Healthcare, Winnipeg, Manitoba, Canada; 4Siemens Healthcare, San Francisco, CA, United States; 5National Institutes of Health, Bethesda, MD, United States; 6Siemens Healthcare, Chicago, Il, United States

We present a new approach to 3D myocardial first-pass perfusion imaging. The technique uses EKG-gated SSFP sequence such that data is acquired only during mid-diastole, whereas the magnetization is maintained in steady-state at other times. TWIST acquisition scheme is combined with GRAPPA to achieve the desired acceleration; the dynamic 3D frames were then motion-corrected using 3D non-rigid registration. Finally, pixel-wise contrast enhancement ratio (CER) images were generated to improve visualization.