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Abstract #3913

Quantification of Pulse Wave Velocity from Phase-Contrast MRI Data Using Fourier Analysis

Nikhil Jha1, Wei Zha1, Himanshu Gupta2, Steven Lloyd2, Thomas S. Denney1

1Auburn University, Auburn, AL, United States; 2University of Alabama at Birmingham, Birmingham, AL, United States

Currently pulse wave velocity (PWV) is measured using the transit time between two corresponding points in respective velocity profiles. The coarse temporal resolution of PC-MRI and change in waveform shape make it difficult to calculate PWV reliably. A frequency domain approach to the measurement of transit time is presented where the Fourier transform of the velocity profiles are taken. The quotient of the two transforms have a linear phase characteristic where the slope is a function of transit time. This method was implemented and found to be more robust in response to changes in the measured velocity wave.