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Abstract #3917

Modeling and Simulation Framework for Hemodynamic Assessment of Aortic Coarctation Patients

Kristof Ralovich1, 2, Viorel Mihalef2, Puneet Sharma2, Lucian Itu3, Dime Vitanovski2, Razvan Ionasec2, Michael Suehling2, Allen Everett4, Giacomo Pongiglione

1Computer Aided Medical Procedures, TU Munich, Munich, Germany; 2Siemens Corporate Research, Princeton, NJ, United States; 3Universitatea Transilvania, Brasov, Romania; 4Johns Hopkins University; 5Ospedale Pediatrico Bambino Gesu, Rome, Italy

We present an integrated modeling and simulation framework for hemodynamic analysis of coarctation patients (post-stenting). 3D anatomical and 2D PC-MRI images are automatically processed to obtain the patient-specific anatomy and flow measurements, which are then used for performing patient-specific Computational Fluid Dynamics (CFD) simulations. A novel coupling of axi-symmetric 1D and 3D CFD unsteady simulations provides physiological boundary conditions for the overall simulation framework. As a first validation study, we compared the simulated and PC-MRI distal aortic flow rate in six patients. The promising initial results reiterate the potential of CFD simulations to provide assessment of post operative hemodynamics.