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Abstract #3941

Evaluation of the Relationship Between Right Ventricle Mechanics and Pulmonary Artery Vessel and Flow Dynamics in Pulmonary Artery Hypertension by MRI

El-Sayed H. Ibrahim1, Abubakr A. Bajwa2

1Department of Radiology, University of Florida, Jacksonville, FL, United States; 2Department of Medicine, University of Florida, Jacksonville, FL, United States

This study investigates the relationships between right-ventricle (RV)-related and pulmonary-artery (PA)-related parameters using MRI. A comprehensive MRI exam was developed for evaluating RV and PA, and tested on 25 PA hypertension(PAH) patients. Standard non-MRI measurements were collected. Comprehensive statistical analysis was conducted to study relationships between parameters, parameters significance, and data redundancy and reduction. The results showed strong correlations between most RV and PA parameters; and between most MRI parameters and PA pressure. There were redundancies between some within-group parameters. In conclusion, RV and PA are coupled and negatively affected in PAH. Both entities should be evaluated and interpreted together.